Trial information
PROTECT Study: A Study of Pro-Brain Natriuretic Peptide (Pro-BNP) Targeted Therapy in Patients with Congestive Heart Failure (CHF) Followed as Outpatients.
Status: Recruiting
Protocol number: 2003-18
Sponsor: Roche Diagnostics
Company division: Diagnostic
Brief summary: This study will evaluate the effect of standard of care plus proBNP compared with standard of care alone for evaluation and medical management of patients with CHF.
Study type: Interventional study
Condition: Congestive Heart Failure
Intervention type: Diagnostic Test
Intervention name: proBNP
Inclusion criteria:
- adult patients >=21 years of age;
- heart failure;
- hospital admission, emergency department visit, or outpatient treatment escalation for heart failure 6 months before enrollment.
Exclusion criteria:
- inoperable aortic valvular heart disease;
- cardiac transplantation or revascularization indicated or expected within 6 months;
- severe obstructive or restrictive pulmonary disease;
- coronary revascularization (ie, percutaneous coronary intervention or coronary artery bypass surgery) within previous 3 months;
- severe renal insufficiency.
Gender: Males or Females
Accepts healthy volunteers: No
Anticipated start date: October, 2005
Trial registration date: 06/24/2005
Date last updated: 11/21/2008
Link to trial result
This trial is being conducted at the following locations:
United States
